Esteem is comprised of a patented formula containing all-natural terpenes and premium Hemp-Derived CBD. It is intended to help prevent the progression of inflammation and has symptom relief capabilities caused by respiratory conditions.


Esteem contains 30 individual terpenes that are all-natural, highly purified, and immune-boosting. Terpenes have been proven for their potent anti-inflammatory properties by inhibiting different biochemical mechanisms in the body’s inflammation process. This formulation can prevent inflammation progression and has symptom relief capabilities caused by respiratory conditions. Results show that the addition of CBD makes the formulation twice as effective, due to the additional anti-inflammatory properties. This formulation has zero psychoactive properties.

One of the main components of Esteem is the addition of NT-VRL proprietary formula. The NT-VRL data-driven formulation is aimed for treating diverse inflammatory conditions, such as the “Cytokine Storm” syndrome seen in COVID-19 patients. According to Forbes and Health Europa, Eybna performed an in vitro immunology evaluation of NT-VRL™. The primary goal of this study was to assess the effect of the formulation on cytokine secretion levels in human immune system resembling the cytokine storm in the human body. Cytokine storms impact cell communication and can both promote and deter inflammation – when released in large amounts they can cause multisystem organ failure. Recent studies have provided evidence that CBD may reduce cytokine storm and inflammation in COVID-19.


The immunologic assay included evaluation of the effect of the test compounds (in different concentrations) on the in vitro cytotoxicity and cytokine production. Experiments were conducted on commercial human peripheral blood mononuclear cells (PBMCs) from two healthy donors. Results of the LPS-induced cytokine assay show that NT-VRL™ had a dose-dependent inhibitory effect on the secretion of pro-inflammatory cytokines, without compromising cell viability.

For more information, please visit:


Health Europa

Study: In Search of Preventative Strategies: Novel Anti- Inflammatory High-CBD Cannabis Sativa Extracts Modulate ACE2 Expression in COVID-19 Gateway Tissues


Fill the dropper with Esteem

Dispense 5 drops underneath your tongue

Image by Mathilde Langevin

Hold the liquid in your mouth for a few seconds, then swallow

You may rinse your mouth out with water afterwards